ZK-261991 is an orally active inhibitor of VEGFR tyrosine kinase(IC50 of 5 nM, VEGFR2).

ZK-261991 inhibits cellular receptor autophosphorylation in KDR-PAECs(IC50 of 2 nM). ZK991 inhibits VEGFR-3 autophosphorylation concentration dependently(IC50 of 20 nM).

886563-25-3

C24H25N7O2

443.5

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years