PIM1-IN-1 is a potent and highly selective inhibitor of PIM1/3(IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively),with Antiproliferative and anti-cancer activity.

PIM1-IN-1 induces apoptosis in SKMEL19 cells[1].

PIM1-IN-1 shows cceptable clearance of 1.26 L/h/kg in BALB-C mice[1].

1417630-95-5

C25H30N8O2

474.56

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years