LSD1-IN-7 benzenesulfonate 是一种有效的口服活性赖氨酸特异性去甲基化酶 1 (LSD1) 抑制剂,IC50为 0.25 nM,具有抗癌活性。它诱导急性髓细胞性白血病和小细胞肺癌细胞分化,对 LSD2、MOA-A 和 MAO-B 的酶抑制作用较小。
产品描述
LSD1-IN-7 benzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.
体内活性
LSD1-IN-7 in combination with other LSD1 inhibitor can be treatment of cancer in a mammal, including breast cancer, lung cancer, prostate cancer, glioblastoma, or leukemia.
Cas No.
2097523-60-7
分子式
C30H29F2N5O5S
分子量
609.64
别名
LSD1-IN-7 benzenesulfonate;CC-90011 benzenesulfonate
储存和溶解度
DMSO:60mg/ml(98.42mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years