DCLX069 是一种选择性蛋白精氨酸甲基转移酶 1 抑制剂，IC50值为 17.9 μM，对 PRMT4 和 PRMT6 的活性较低。它可有效阻断乳腺癌、肝癌和急性髓性白血病细胞系中的细胞增殖。

DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17.9 μM. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver cancer, and acute myeloid leukemia cell lines.

792946-69-1

C20H25N3O2

339.43

DCLX 069;DCLX-069

DMSO:60 mg/ml (176.77 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years