WM-3835 是一种高特异性HBO1(KAT7orMYST2) 抑制剂，可直接与 HBO1 33 的乙酰辅酶 A 结合位点结合 WM-3835 激活细胞凋亡，抑制骨肉瘤细胞的增殖，迁移和侵袭。它抑制小鼠中骨肉瘤异种移植物的生长，有抗肿瘤活性。

WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation.

WM-3835, a novel and high-specific small molecule HBO1 inhibitor, was able to potently suppressed OS cell proliferation and migration, and led to apoptosis activation.

2229025-70-9

C20H17FN2O4S

400.42

DMSO:250 mg/mL (624.34 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years