您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > 3-Deazaneplanocin A
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
3-Deazaneplanocin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-Deazaneplanocin A图片
CAS NO:102052-95-9
包装与价格:
包装价格(元)
100 mg电议
500 mg电议

产品介绍
3-Deazaneplanocin A 是组蛋白甲基转移酶(EZH2)和 S-腺苷同型半胱氨酸水解酶 (AHCY) 抑制剂。

产品描述

3-Deazaneplanocin A (DZNep) is an attractive epigenetic anticancer agent through the inhibition of the cellular enhancer of zeste homolog 2 (EZH2) protein.

体外活性

Continuous exposure for 14 days to tubercidin alone is highly toxic to both human CFU-GM and BFU-E. The IC50s of tubercidin are 3.4±1.7 and 3.7±0.2 nM for CFU-GM and BFU-E, respectively. Tubercidin also has a direct dose-dependent inhibitory effect on myeloid and erythroid human bone marrow progenitor cells in vitro[1].

Cas No.

102052-95-9

分子式

C12H14N4O3

分子量

262.269

储存和溶解度

DMSO:75 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years