产品描述
GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively). GSK9311 is a less active analog of GSK6853. It can be used as a negative control.
体外活性
GSK6853 is a less active analogue of GSK6853 in which the 5-amide is alkylated. GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain. GSK6853 shows properties suitable for cellular and in vivo studies[1].
Cas No.
1923851-49-3
分子式
C24H31N5O3
分子量
437.53
储存和溶解度
DMSO:30 mg/mL (68.57 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years