产品描述
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potential to treat diabetic disease.
体内活性
Fidarestat (1 or 4 mg/kg. p.o., daily for 4 weeks) decreases the concentrations of sorbitol and fructose in diabetic rats [2].
Cas No.
136087-85-9
分子式
C12H10FN3O4
分子量
279.22
别名
SNK 860
储存和溶解度
DMSO:250 mg/mL (895.35 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years