BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1].

BI 99179 is potent in the mouse hypothalamic N-42 cell with an IC50 of 0.6 μM and it shows no significant LDH release in the cytotoxicity assay up to 30 μM[1].

BI 99179 has a super pharmacokinetic profile in male Han/Wistar rats (oral application of 4 mg/kg)with half life (t1/2) of 3.0 h[1].

1291779-76-4

C23H25N3O3

391.46

BI99179

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years