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(±)-Equol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:94105-90-5
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
Equol
(R,S)-Equol
(±)-雌马酚
产品介绍
(±)-Equol 是 equol 的外消旋体。它对 ERα 和 ERβ 的EC50s of 分别为 200 和 74 nM。Equol是大豆异黄酮黄豆苷和大豆黄素的代谢产物。

产品描述

Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein. (S)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM). (S)-equol is also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies.

Cas No.

94105-90-5

分子式

C15H14O3

分子量

242.3

别名

Equol;(R,S)-Equol;(±)-雌马酚

储存和溶解度

DMSO:100 mg/mL (412.76 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years