Monomethyl fumarate 是 Dimethyl fumarate 的活性代谢产物。Monomethyl fumarate是一种GPR109A 激动剂。Monomethyl fumarate是一种GPR109A 激动剂具有用于多种神经保护途径和其他视网膜疾病模型的潜力。

Monomethyl fumarate is a potent agonist of GPR109A .

Monomethyl fumarate (25 μM; 24?hours) attenuates 7β-OHC-induced cytotoxicity: cell growth inhibition; decreased cell viability; mitochondrial dysfunction; and cell death induction[3].

2756-87-8

C5H6O4

130.1

DMSO:90 mg/mL (691.78 mM),Need ultrasonic
H2O:8 mg/mL (61.49 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years