SR2211 is a potent and selective synthetic RORγ modulator (Ki: 105 nM and an IC50: ~320 nM).

The expression of the IL-23 receptor is significantly inhibited by SR2211. Treatment of EL-4 cells with SR2211 causes significant inhibition of IL-17 intracellular staining as compared to vehicle-treated cells [1].

1359164-11-6

C26H24F7N3O

527.48

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years