Xenin 8 acetate 是神经降压素/异视素家族中 Xenin 的生物活性片段。 Xenin 8 acetate 增强精氨酸诱导的胰岛素释放(40%)并增强胰高血糖素对精氨酸(60%)和卡巴胆碱(50%)的反应。
产品描述
Xenin 8 acetate is a biologically active fragment of Xenin in the neurotensin/xenopsin family. Xenin 8 acetate augments Arginine-induced insulin release (by 40%) and potentiates the glucagon responses to both Arginine (by 60%), Carbachol (by 50%).
体外活性
Xenin 8 acetate stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner with an EC50 of 0.16 nM. Xenin 8 acetate counteracts the inhibition of glucagon release induced by increasing the glucose concentration[1].
Cas No.
TP2209L
分子式
C53H83N15O11
分子量
1106.32
别名
Xenin 8 acetate (117442-28-1 Free base)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years