Olesoxime 是一种靶向线粒体的神经保护性试剂,能够促进细胞存活,其EC50=3.2±0.2 μM。
产品描述
Olesoxime (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.
体内活性
Olesoxime, a molecule from a novel "cholesterol-oxime" family of cytoprotective compounds identified based on survival promoting activities on trophic factor deprived motor neurons shows neuroprotective and neuroregenerative effects in five animal models of motor nerve degeneration[1].
Cas No.
22033-87-0
分子式
C27H45NO
分子量
399.663
别名
TRO 19622;奥利索西;NSC 21311
储存和溶解度
DMSO:51 mg/mL (127.61 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years