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Perhexiline maleate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Perhexiline maleate图片
CAS NO:6724-53-4
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Perhexiline maleate是肉碱棕榈酰转移酶1抑制剂,对大鼠心脏和肝脏CPT 1的IC50值分别为77 和 148 μM。

产品描述

Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT 1) (rat heart and liver CPT 1 with IC50s of 77 and 148 μM , respectively).

体外活性

Perhexiline treatment increases the susceptibility of NB cells to antiblastic treatments. Co-administration of Perhexiline maleate potentiates the efficacy of cisplatin to reduce the in vitro clonogenic potential of NB cells[2].

体内活性

The co-administration of Perhexiline and cisplatin yields a clear enhancement of antitumor effects, resulting in a significantly improved progression-free survival as compared with mice treated with DMSO.

Cas No.

6724-53-4

分子式

C23H39NO4

分子量

393.56

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years