PolmaCOXib是一流的 NSAID 候选药物,是碳酸酐酶 (CA) 和 COX-2 的双重抑制剂。它在小鼠模型中抑制大肠腺瘤和肿瘤生长。
产品描述
Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.
Cas No.
301692-76-2
分子式
C18H16FNO4S
分子量
361.39
别名
CG-100649;CG100649;帕马考昔;CG 100649
储存和溶解度
DMSO:55 mg/ml (152.19 mM)
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years