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Cecropin B acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cecropin B acetate图片
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
Cecropin B acetate(80451-05-4 Free base)
产品介绍
Cecropin B acetate 通过破坏 PXR/类视黄醇 X 受体 α (RXR-α) 复合物与 DNA 序列的结合来诱导 NF-Κb 活化并抑制 CYP3A29。 Cecropin B acetate 具有很强的抗菌活性。

产品描述

Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA sequences. Cecropin B acetate exhibits strong antimicrobial activity.

体外活性

Cecropin B acetate activates pig liver cells by interacting with TLRs 2 and 4, which modulated NF-κB-mediated signaling pathways[1].

体内活性

The wounds were moist with more exudation in C group,while that in other groups were dry without obvious exudation. The body temperature of the majority of the mice in each group were elevated, but the number of leucocytes in each group was lowered after operation. The quantity of bacteria in muscle in A group[ (42 +/- 50) CFU/g] was obviously lower than that in M group [(886+/-804) CFU/g, P<0.05] , and it was all obviously lower than that in C group[ (41 +/-28) x 10(5) CFU/g, P<0.01]. The number of surviving mice after 4 PID in C group was evidently smaller than that in A and M groups( P<0. 05)[2].

别名

Cecropin B acetate(80451-05-4 Free base)

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years