WAY-213613 是选择性非底物再摄取GLT-1/EAAT2抑制剂，对 EAAT2 的IC50为 85 nM。它对 EAAT1 和 EAAT3 的选择性是 59 倍和 44 倍，IC50分别为 5 和 3.8 μM。它是阐明 EAAT2 功能的潜在工具。

WAY-213613 is a potent and selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 (IC50: 85 nM EAAT2). It displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s: 5 and 3.8 μM, respectively). WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors.

868359-05-1

C16H13BrF2N2O4

415.19

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years