hDHODH-IN-5 是人源二氢乳清酸脱氢酶的抑制剂 (hDHODH, IC50 = 0.91 μM)。
产品描述
hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).
体外活性
hDHODH-IN-5 induces differentiation in ER-HOX-GFP, THP1, and U937 human AML cell lines with EC50s of 3.6, 2.7, and 2.5 μM, respectively[1].
Cas No.
2029049-77-0
分子式
C21H21F3N2O2
分子量
390.4
储存和溶解度
DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years