(Rac)-BMS-816336 (Compound 6n) 是 BMS-816336 的外消旋体。(Rac)-BMS-816336 是人和小鼠 11β-羟类固醇脱氢酶 1 型 (11β-HSD1) 的有效抑制剂，其IC50分别为 10 nM 和 68 nM，并具有良好的代谢稳定性 。

(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme inhibitor with IC 50 s of 10 nM and 68 nM, respectively. (Rac)-BMS-816336 has good metabolic stability [1].

(Rac)-BMS-816336 (compound 6n) has good metabolic stability with the remaining rates in human, mouse and rats of 88%,82% and 72%, respectively [1].

T12663

C21H27NO3

341.44

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years