Praziquantel 是一种外消旋混合物，由 (R)-Praziquantel 和 (S)-Praziquantel 组成。它可研究血吸虫病。

Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.

55268-74-1

C19H24N2O2

312.42

Pyquiton;吡喹酮;Droncit;Biltricide

DMSO:59 mg/mL (188.8 mM)
Ethanol:59 mg/mL (188.8 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years