Bortezomib-pinanediol 是一种蛋白酶体抑制剂。是硼替佐米的前药。

Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.

Bortezomib-pinanediol (BP)-loaded HA-CCMs exhibit markedly enhanced toleration, broadened therapeutic window, and significantly more effective growth suppression of CD44-overexpressed multiple myeloma in nude mice than free bortezomib.?Lipophilized BTZ-loaded HA-CCMs has opened a new avenue for targeted bortezomib therapy of multiple myeloma.

205393-22-2

C29H39BN4O4

518.47

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years