Alloxan Monohydrate 是一种能够引起糖尿病的致糖尿病药物。它作为蛋白酶体抑制剂,破坏胰腺中能够分泌胰岛素的B细胞,导致实验动物患糖尿病。
产品描述
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
体外活性
Alloxan caused the accumulation of ubiquitinated proteins in NRK cells through the inhibition of the proteolytic activities of the proteasome.?Alloxan directly acts on the chymotrypsin- and trypsin-like peptidase activities[1]
Cas No.
2244-11-3
分子式
C4H4N2O5
分子量
160.085
储存和溶解度
DMSO:5mg/ml(31.23mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years