Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and also inhibits the lysosomal enzyme cathepsin A.

After injection in young and adult mice, Lactacystin (microinjection; 2 μg) causes a Parkinson's disease-like motor phenotype 5-7 days [2].

133343-34-7

C15H24N2O7S

376.43

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years