NPPB 是外向整流氯化物通道阻断剂,IC50 为 80 nM。
产品描述
NPPB is a chloride channel blocker with IC50 of 80 nM .
体外活性
NPPB has been shown to activate the GPR35-Gαi/o and GPR35-Gα16 pathways in HEK293 cells, inducing intracellular calcium mobilization[1].
Cas No.
107254-86-4
分子式
C16H16N2O4
分子量
300.31
储存和溶解度
DMSO:150 mg/mL (499.48 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years