Tolperisone hydrochloride 是中枢作用肌肉松弛剂，可用于研究神经疾病引起的病理性横纹肌硬化（锥体束损伤、脊髓病、多发性硬化症、脑脊髓炎）、痉挛性麻痹及其他肌肉张力障碍相关的脑病。

Tolperisone hydrochloride, a centrally acting muscle relaxant, is used in the therapy of pathologically increased tone of the cross-striated muscle resulted by neurological diseases (damage of the encephalomyelitis, myelopathy, multiple sclerosis, pyramidal tract) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.

Tolperisone hydrochloride是一种安全有效的治疗疼痛反射性肌肉痉挛的药物,且没有中枢性肌肉松弛药的典型副作用。Tolperisone可以阻断蜗牛神经元的钙离子流,降低青蛙郎氏节处钠钾离子渗透性,并且对电流通过Nav1.6通道（异源表达）有抑制作用。

3644-61-9

C16H24ClNO

281.82

Tolperisone HCl;盐酸托哌酮;Midocalm;托哌酮盐酸盐;Muscalm

DMSO:52 mg/mL (184.5 mM)
Ethanol:52 mg/mL (184.5 mM)
H2O:51 mg/mL (181 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years