Triclabendazole是一种苯并咪唑,与微管蛋白结合,损害细胞内运输机制,且干扰蛋白质的合成。
产品描述
Triclabendazole has been used in trials studying Parasitic Disease.
体外活性
Triclabendazole treatment produces percentage decreases of the fluke egg output by 15.3%, 4.3% and 36.6%, respectively, in sheep, dairy cows and heifers, these results indicate the presence of TCBZ-resistant Fasciola hepatica in sheep and cattle on this farm. [1] Triclabendazole sulphoxide (50 mg/mL) results in extensive damage to the tegument of triclabendazole-susceptible F. hepatica, whereas triclabendazole-resistant flukes shows only localized and relatively minor disruption of the tegument covering the spines. [2]
Cas No.
68786-66-3
分子式
C14H9Cl3N2OS
分子量
359.65
别名
三氯苯达唑;CGA89317;三氯苯咪唑
储存和溶解度
DMSO:67 mg/mL (186.3 mM)
H2O:<1 mgml
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years