Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic HCV infection.

In the chimpanzee, Valopicitabine (NM 283) has potent antiviral activity against chronic hepatitis C virus genotype-1 [1].In Sprague-Dawley rats, Valopicitabine exhibits moderate Cmax (3.62 ug/mL) and terminal elimination half-lives (T1/2 0.64 h) following oral administration (100 mg/kg) [2].

640281-90-9

C15H24N4O6

356.37

NM283

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years