PSN 375963 hydrochloride 是GPR119激动剂，对人和小鼠的EC50分别为 8.4 和 7.9 μM。它表现出与内源性油酰乙醇酰胺 (OEA) 相似的效力。

PSN 375963 hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.

PSN 375963 is a potent GPR119 agonist with EC50s of 8.4 and 7.9 μM for human and mouse GPR119[1].

PSN 375963 suppressed food intake in rats and reduced body weight gain and white adipose tissue deposition upon subchronic oral administration to high-fat-fed rats[2].

388575-52-8

C17H23N3O

285.38

PSN 375963 hydrochloride

Ethanol:24 mg/ml(74.57 mM)
DMSO:4 mg/ml(12.43 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years