Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).

L-selectin shedding from mouse and human lymphocytes inhibited by Ro 31-9790, Jurkat T cells, and human monocytes(IC50 of 0.3-0.4 μM on these cell types.) The IC50 values obtained for Ro 31-9790 are 4.82?±?0.75 μM, 1.16?±?0.27 μM, 0.70?±?0.06 μM, 4.47±?1.27 μM and 0.38?±?0.05 μM for mouse lymphocyte L-selectin shedding, Jurkat L-selectin shedding, human lymphocyte L-selectin shedding, human monocyte L-selectin shedding and human monocyte TNF-α shedding.

145337-55-9

C15H29N3O4

315.41

GI4747

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years