产品描述
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.
体外活性
ZM223 hydrochloride (0.1-1 μM; 4 hours) inhibits both HCT-116 and U-2OS cancer cells(IC50s of 100 and 122 nM, respectively).
Cas No.
T13412L
分子式
C23H18ClF3N4O2S2
分子量
538.99
别名
ZM223 hydrochloride
储存和溶解度
DMSO:150 mg/mL (278.30 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
m.cnreagent.com
