PIK293 是一种 IC87114 的类似物，是一种 PI3K 的抑制剂，其对p110δ (IC50:0.24 μM)、p110β (IC50:10 μM)、p110γ (IC50:25 μM) 和 p110α (IC50:100 μM)。

PIK-293 is a PI3K inhibitor, for PI3Kδ( IC50=0.24 μM), and less potent for PI3Kα/β/ γ.

PIK-293 is a pyrazolopyrimidine analog of IC87114. PIK-293 is synthesized by replacing the adenine of IC87114 with the isosteric pyrazolopyrimidine. [1]

900185-01-5

C22H19N7O

397.43

PIK293

DMSO:80 mg/mL (201.29 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years