CHK1-IN-4 is a potent inhibitor of checkpoint kinase 1 (chk1) and potently inhibits chk1 phosphorylation in the tumor cells with anti-tumor activity.

CHK1-IN-4 (Compound 3; 40 mg/kg, i.v., twice a week) alone enhances the anti-tumor growth activity of CPT1 in the tumor model.

2120398-41-4

C18H18BrN7O2

444.29

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years