Aminopurvalanol A 是一种竞争性、选择性和细胞渗透性的Cyclins/CDK复合物抑制剂，优先靶向G2/M 期转变进而抑制癌细胞分化。它通过抑制生理获能依赖性肌动蛋白聚合而抑制精子受精能力。

Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1, Cyclin E/cdk2, and P35/cdk5 with IC50 of 33 nM, 33 nM, 28 nM and 20 nM, respectively.

220792-57-4

C19H26ClN7O

403.91

DMSO:30 mg/ml (74.27mM),Need ultrasonic
Ethanol:10 mg/ml (24.76mM）,Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years