BI-1347 是一种有效的、选择性的 CDK8/cyclinC 抑制剂，IC50值为 1 nM，可抑制肿瘤生存，详细信息请参考 WO2017202719A1 中的产物 I-003。

BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.

2163056-91-3

C22H20N4O

356.429

DMSO:120 mg/mL (336.68 mM)),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years