GLPG2938 是一种选择性S1P2拮抗剂，可用于特发性肺纤维化的研究。
产品描述
GLPG2938 is a potent and selective antagonist of S1P2.
体外活性
GLPG2938 significantly prevents the S1P-mediated contraction at all tested concentrations[1].
体内活性
In all species ,GLPG2938 shows good pharmacokinetics, with long half-life,low clearance,and good bioavailability.
Cas No.
2130996-00-6
分子式
C20H19F6N7O2
分子量
503.409
别名
1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea
储存和溶解度
DMSO:60 mg/ml (119.19 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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