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Epidermal Growth Factor Receptor Peptide Acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)
产品介绍
Epidermal Growth Factor Receptor Peptide Acetate 存在于细胞表面,通过与其特异性配体的结合而被激活。EGFR 属于受体酪氨酸激酶 (RTK) 的 ErbB 家族。

产品描述

Epidermal Growth Factor Receptor Peptide exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK).

体外活性

This autophosphorylation elicits downstream activation and signaling by several other proteins that associate with the phosphorylated tyrosines through their own phosphotyrosine-binding SH2 domains.?These downstream signaling proteins initiate several signal transduction cascades, principally the MAPK, Akt and JNK pathways, which lead to DNA synthesis and cell proliferation.Such proteins modulate phenotypes such as cell migration, adhesion, and proliferation.?Activation of the receptor is important for the innate immune response in human skin.?

Cas No.

T21723L

分子式

C63H97N13O25

分子量

1436.52

别名

Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)

储存和溶解度

H2O:10 mg/mL (7.27mM)
DMSO:133mg/mL(96.62mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years