Fast Green FCF 是海绿色三芳基甲烷食用染料，最大吸收在625nm处，将在电泳过程中的蛋白质染色，。

Fast Green FCF, a safe biocompatible color additive, has been suggested to mitigate chronic pain.

Pretreatment of Fast green FCF (100 mg/kg, i.p. daily for 7 days) alleviated depressive-like behavior in LPS-treated mice.?Fast green FCF suppressed the LPS-induced microglial and astrocyte activation in the hippocampus.?Fast green FCF decreased the mRNA and protein levels of Toll-like receptor 4 (TLR4) and Myeloid differentiation primary response 88 (Myd88) and suppressed the phosphorylation of nuclear factor-κB (NF-κB) in the hippocampus of LPS-treated mice.?Fast green FCF also downregulated hippocampal tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6, but did not alter the level of the brain-derived neurotrophic factor (BDNF) in the hippocampus of LPS-treated mice.?The molecular docking simulation predicts that Fast green FCF may interact with TLR4 and interrupt the formation of the TLR4-MD2 complex[1].

2353-45-9

C37H34N2Na2O10S3

808.84

Food green 3;固绿 FCF;FD&C Green No. 3;C.I. 42053

H2O:10 mg/mL (12.36 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years