DSS Crosslinker 是一种不可切割的 ADC 连接剂,用于合成抗体-药物偶联物。
产品描述
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins.
体外活性
ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker.
Cas No.
68528-80-3
分子式
C16H20N2O8
分子量
368.34
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years