Succinic anhydride 是来自专利 WO2009064913A1 中的环状酸酐和不可裂解的 ADC 接头。它可以与专利的化合物 4 反应，将前药连接到靶向多肽的胺或羟基 1 基团。

Succinic anhydride is a cyclic anhydride extracted from patent WO2009064913A1. Succinic anhydride acts as a nonclaevable ADC linker. Succinic anhydride can react with compound 4 of the patent to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide.

108-30-5

C4H4O3

100.07

DMSO:100 mg/mL (999.30 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years