m-PEG12-OH 是一种基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。它也是一种不可切割的 12 单元 PEG ADC 接头，用于合成抗体-药物偶联物。

m-PEG12-OH is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

2050595-03-2

C25H52O13

560.67

Dodecaethylene Glycol Monomethyl Ether

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years