Deruxtecan 是一种 ADC 药物-接头偶联物，由 DX-8951 (DXd) 的衍生物和马来酰亚胺-GGFG 肽接头组成，用于合成 DS-8201 和 U3-1402。

Deruxtecan is an ADC drug-linker conjugate consisting of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker for the synthesis of DS-8201 and U3-1402.

Antibody-drug conjugates deliver anticancer agents selectively and efficiently to tumor tissue which have significant antitumor efficacy with a wide therapeutic window[2].

1599440-13-7

C52H56FN9O13

1034.05

DMSO:34 mg/mL (32.88 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years