(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

HaloPROTACs are designed to induce ubiquitylation and degradation of HaloTag7 fusion proteins[1].

1835705-59-3

C40H63ClN4O10S

827.47

VHL Ligand-Linker Conjugates 10;VH032-PEG6-C4-Cl;E3 ligase Ligand-Linker Conjugates 9

DMSO:100 mg/mL (120.85 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years