Amorolfine hydrochloride是一种抗真菌剂。

Amorolfine Hydrochloride is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase. These enzymes can deplete ergosterol and cause ignosterol to accumulate in the fungal cytoplasmic cell membranes.

78613-38-4

C21H36ClNO

353.97

Amorolfine HCl;Amorolfin;Ro 14-4767/002;盐酸阿莫洛芬;盐酸阿莫罗芬

DMSO:27 mg/mL (76.3 mM)
H2O:9 mg/mL (25.42 mM)
Ethanol:66 mg/mL (186.5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years