2-Fluoroadenine 对非增殖性和增殖性肿瘤细胞具有毒性。2-Fluoroadenine 可用于抗癌症的相关研究。

2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.

In Balb-3T3 cells, 2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses. In CEM cells, 2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis. In nonproliferating MRC-5 cells, 2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity[2].

700-49-2

C5H4FN5

163.12

NSC-27364;NSC 27364;NSC27364;2-氟腺嘌呤

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years