TAT源自人免疫缺陷病毒的转录反式激活因子，是一种细胞穿透肽。它可以增加异源蛋白质的产量和溶解度。

TAT (YGRKKRRQRRR) is a cell-penetrating peptide derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1). TAT can increase the yields and the solubility of heterologous proteins[1].

TAT (YGRKKRRQRRR) represents amino acids 47-57 of the human immunodeficiency virus type I (HIV-1) TAT protein. The positively charged protein transduction domain of the HIV-1 TAT protein (TAT-PTD; residues 47-57 of TAT) rapidly translocates across the plasma membrane of living cells. This property is exploited for the delivery of proteins, drugs, and genes into cells. TAT (YGRKKRRQRRR; TAT-PTD) can cross the hydrophobic lipid bilayer of a cell membrane simply by passive diffusion[1].

191936-91-1

C64H118N32O14

1559.858

H2O:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years