4-Hydroxychalcone 是一种查尔酮代谢物，具有抗血管生成和消炎作用。它抑制 TNF-α 诱导的NF-Κb途径活化并激活BMP信号传导，通过减轻小鼠的醛固酮过多症和肾脏损伤来降低抵抗性高血压。它通过抑制生长因子途径抑制血管生成，无细胞毒性迹象。

4-Hydroxychalcone attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.

20426-12-4

C15H12O2

224.259

P-Cinnamoylphenol;4-羟基查尔酮

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years