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Hydrocortisone cypionate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hydrocortisone cypionate图片
CAS NO:508-99-6
包装:50 mg
市场价:8174元

产品介绍

产品描述

Hydrocortisone cypionate is a corticosteroid ester and synthetic glucocorticoid corticosteroid.

体外活性

Hydrocortisone-treated DCs inhibit production of IFN-γ but induce an increased release of IL-4 and no change in IL-5.?Hydrocortisone reduces postischemic oxidative stress, perfusion pressure, and transudate formation.?Hydrocortisone inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan as is release of histamine from resident mast cells.Hydrocortisone (50 nM) shows a dose-dependent down-regulation of GR transcript in hCMEC/D3 cells. Hydrocortisone supplementation of the serum-reduced cell differentiation medium leads to a significant increase in TER across the hCMEC/D3 monolayer. Hydrocortisone-treated Dendritic cells (DCs) show a decreased expression of MHC II molecules, the costimulatory molecule CD86, and the DC-specific marker CD83, as well as a strongly reduced IL-12 secretion.

Cas No.

508-99-6

分子式

C29H42O6

分子量

486.64

储存和溶解度

DMSO:125 mg/mL (256.86 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years