Butyl isobutyl phthalate 是一种非竞争性 α-葡萄糖苷酶抑制剂,IC50=38 μM,可以从海带的根状茎中分离得到。它具有降血糖作用,可用于糖尿病相关的研究。
产品描述
Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM),it shows a hypoglycemic effect
体内活性
Butyl isobutyl phthalate(BIP) could be considered as an α-glucosidase inhibitor and developed as an important antidiabetes agent for type II diabetes therapy.
动物实验
Animal Model:Streptozocin induced diabetic mice (Male Kunming mice). Dosage:25, 50 or 100 mg/kg, Administration:Intragastric administration
Cas No.
17851-53-5
分子式
C16H22O4
分子量
278.348
别名
邻苯二甲酸-1-丁酯-2-异丁酯;ButylIsobutylPhthalate
储存和溶解度
DMSO:250 mg/mL (898.18 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years