BRD0418作为TRIB1表达的上调因子，导致肝脏脂蛋白代谢从脂肪生成到清除的重新编程。

BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.

Treatment of HepG2 cells with BRD0418 for 6 hours resulted on average in 3.5-fold up-regulation of TRIB1 transcript levels, with half-maximal effect achieved at 2.3 μM concentration of the compound[1].

1565827-99-7

C29H32N2O5

488.57

BRD-0418;BRD 0418

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years